Generation of MK clones showing different degrees of differentiation.

Figshare2015-12-02 更新2026-04-29 收录

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Generation of MK clones showing different degrees of differentiation.

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2015-12-02

Gene expression data from human erythroleukemic cells in a time dependent manner after PMA treatment

巨核细胞分化

依赖性基因表达

The molecular regulation of megakaryocytic differentiation is poorly understood. Using a myelogenous leukemia cell line, K562, which can partly recapitulate the process in response to phorbol 12-myri

NIAID Data Ecosystem100

Megakaryocyte lineage development is controlled by modulation of protein acetylation

巨核细胞分化

蛋白质乙酰化与去乙酰化

Treatment with lysine deacetylase inhibitors (KDACi) for haematological malignancies, is accompanied by haematological side effects including thrombocytopenia, suggesting that modulation of protein ac

NIAID Data Ecosystem80

Data for: Unequal distribution of genes and chromosomes refers to nuclear diversification in the binucleated Giardia intestinalis.

寄生虫基因组

巨核细胞分化

The single-celled parasite Giardia intestinalis (Diplomonadida) has two equally sized nuclei in one cell. The nuclei have been considered identical. We have previously shown that they contain differen

NIAID Data Ecosystem60

Inhibition of O-GlcNAcylation via O-GlcNAc transferase fosters megakaryopoiesis and induces thrombopoiesis

巨核细胞分化

血小板生成

We report that cellular O-GlcNAcylation levels decline along the course of megakaryocyte (MK) differentiation from human-derived hematopoietic stem and progenitor cells (HSPCs) and that inhibition of

NIAID Data Ecosystem80

Expression analysis of primary mouse megakaryocyte differentiation. Mus musculus

巨核细胞分化

血小板生成

Megakaryocyte (MK) differentiation is well described in morphologic terms but its molecular counterparts and the basis for platelet release are incompletely understood. We profiled mRNA expression in

NIAID Data Ecosystem80

Generation of MK clones showing different degrees of differentiation.

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