首页/数据集/Cell specific gene silencing of lipid-siRNA conjugates in the mouse central nervous system (CNS)

Cell specific gene silencing of lipid-siRNA conjugates in the mouse central nervous system (CNS)

ChEBI2024-04-30 更新2026-07-12 收录

siRNA治疗

中枢神经系统靶向

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-13964 数据链接链接失效反馈

官方服务：

资源简介：

Cell specific gene silencing of lipid-siRNA conjugates in the mouse central nervous system (CNS)

应用场景：

创建时间：

2024-04-30

siRNA治疗

RNA测序

Examine potential off-target effects of HTT targeting siRNA in cynomologus macaque brains. RNA-seq of brain punches from HTT targeting siRNA treated and non-treated cynomolgus macaques (N=4 per group)

NIAID Data Ecosystem70

Characterization of Hepatitis B Virus Transcripts in Chronically HBV-infected Chimpanzees and Patients Treated with ARC-520 siRNA Demonstrates Transcriptional Silencing of cccDNA

乙型肝炎病毒转录调控

siRNA治疗

Full-length hepatitis B virus (HBV) transcripts of chimpanzees and patients treated with multidose (MD) HBV siRNA ARC-520 and entecavir (ETV) were characterized by single-molecule real-time (SMRT) seq

NIAID Data Ecosystem60

Interferon response in hind limb muscle tissue of C57BL/6 mice after treatment with siRNAs.

干扰素基因表达

siRNA治疗

Mice were treated with siRNA and gene expression changes in interferon alpha, beta and gamma was monitored in hind limb muscle tissues (n = 3 for each treatment) at 24 h, 48 h, 72 h and 96 h p.i.. Res

NIAID Data Ecosystem30

Small Interfering RNA (siRNA)-based Therapeutics Market

siRNA治疗

医药市场

Technological advancements in the Small Interfering RNA (siRNA)-based Therapeutics industry are shaping the future market landscape. The report evaluates innovation-driven growth and how emerging tech

IMR REPORTS70

siRNAs induced long-term liver ApoB mRNA knockdown significantly lowers serum cholesterol in a mouse model with human-like serum lipids . Mus musculus

siRNA治疗

脂质代谢调控

Increased serum apoB and associated low density lipoprotein cholesterol (LDL) levels are well correlated with an increased risk of coronary disease. Apo E-/- and LDLr -/- mice have been extensively us

NIAID Data Ecosystem40

Cell specific gene silencing of lipid-siRNA conjugates in the mouse central nervous system (CNS)

资源简介：

相关数据集