Role of calcium/calmodulin-dependent kinase type IV in podocyte function in lupus nephritis

ChEBI2014-08-01 更新2026-07-21 收录

狼疮性肾炎机制

周细胞分子病理

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-55768 数据链接链接失效反馈

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Role of calcium/calmodulin-dependent kinase type IV in podocyte function in lupus nephritis

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2014-08-01

Glomerulonephritis in BXSB/MpJ-Yaa mice

狼疮性肾炎机制

肾小球肾炎

Analysis of glomeruli isolated from kidneys of 4 month male BXSB/MpJ-Yaa. The BXSB/MpJ-Yaa mouse strain is a lupus-prone model. Results provide insight into the pathogenic mechanisms linked to glomer

NIAID Data Ecosystem80

Table_1_Acute Kidney Injury Induced Lupus Exacerbation Through the Enhanced Neutrophil Extracellular Traps (and Apoptosis) in Fcgr2b Deficient Lupus Mice With Renal Ischemia Reperfusion Injury.pdf

狼疮性肾炎机制

急性肾损伤

Renal ischemia is the most common cause of acute kidney injury (AKI) that might be exacerbate lupus activity through neutrophil extracellular traps (NETs) and apoptosis. Here, the renal ischemia reper

NIAID Data Ecosystem40

Reduction of SIRPa connects podocyte metabolism dysfunction to inflammatory activation via promoting PKM2 nuclear translocation in diabetes nephropathy II

糖尿病机制

周细胞分子病理

A central cause of diabetic nephropathy (DN) is podocyte injury. There are many factors causing podocyte injury in DN, such as hyperglycemia, oxidative stress and inflammation. In this study, a signal

NIAID Data Ecosystem30

RNA expression data from glomeruli lacking von Hippel-Lindau protein in podocytes. Mus musculus

周细胞分子病理

肾小球疾病

We and others have previously shown that glomerular endothelial cells and podocytes express hypoxia-inducible transcription factors (HIFs). HIFs bind to hypoxia response elements in target genes, such

NIAID Data Ecosystem40

Functional characterization of podocyte-expressed THSD7A in experimental membranous nephropathy

膜性肾病机制

周细胞分子病理

While the pathogenic role of autoantibodies targeting the podocyte protein THSD7A in membranous nephropathy (MN) is well described, the consequences of autoantibody binding for podocyte homeostasis an

NIAID Data Ecosystem30

Role of calcium/calmodulin-dependent kinase type IV in podocyte function in lupus nephritis

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