Cu(I)-Catalyzed Reductive Aldol Cyclizations: Diastereo- and Enantioselective Synthesis of β-Hydroxylactones<sup>†</sup>
收藏NIAID Data Ecosystem2026-03-06 收录
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Copper bisphosphine complexes catalyze the intramolecular reductive aldol reaction of α,β-unsaturated esters with ketones, affording five- and six-membered β-hydroxylactones in high stereoselectivities. Utilization of chiral nonracemic bisphosphines render the cyclizations enantioselective.
创建时间：
2016-05-05
