Direct Arylation of Distal and Proximal C(sp³)–H Bonds of <i>t</i>‑Amines with Aryl Diazonium Tetrafluoroborates via Photoredox Catalysis

A visible light-mediated arylation protocol for t-amines has been reported through the coupling of γ- and α-amino alkyl radicals with different aryl diazonium salts using Ru­(bpy)3Cl2·6H2O as a photocatalyst. Structurally different 9-aryl-9,10-dihydroacridine, 1-aryl tetrahydroisoquinoline, hexahydropyrrolo­[2,1-a]­isoquinoline, and hexahydro-2H-pyrido­[2,1-a]­isoquinoline frameworks with different substitution patterns have been synthesized in good yield using this methodology.