We report the gene expression differences between OT-1 T cells activated in the presence of TLR1/2 (Pam3CSK4),TLR3 (Poly I:C), or TLR9 (ODN1826). By activating OT-1 splenocytes in the presence of the
A. Animals were administered i.n. poly I:C (50 µg), TLR7 agonist (imiquimod 50 µg or gardiquimod 50 µg) , or saline vehicle daily for 2 days. Twenty-four hours after the last dose, animals were given
Data represent mean ± SD. n = 3 mice. Significant differences were determined by Student t test. P values obtained from comparing both groups are included in the table.Absolute number (×104) of IL-12