Enables fumarate hydratase activity. Involved in several processes, including fumarate metabolic process; positive regulation of cold-induced thermogenesis; and tricarboxylic acid cycle. Acts upstream
ENCODES a protein that exhibits peptide antigen binding (ortholog); polysaccharide binding (ortholog); T cell receptor binding (ortholog); INVOLVED IN antigen processing and presentation of endogenous
The mutant rat strain was produced by injecting TALEN system targeting the exon 4 of rat Apoe into Sprague Dawley (Hsd:SD) embryos. This mutant rat has a 16-bp deletion in the gene third coding exon)