Effects of montage polarity during 400 Hz cortico-cerebellar transcranial pulsed current stimulation on brain excitability and hand dexterity.

This study compares the effects of two bifocal single session 400 Hz pulsed current stimulation (tPCS) montages, anodal tPCS over M1 with cathodal tPCS over the CB (a-tPCSM1–c-tPCSCB; Montage 1) and cathodal tPCS over M1 with anodal tPCS over the CB (c-tPCSM1–a-tPCSCB; Montage 2), on corticospinal excitability (CSE), corticocortical excitability (CCE), and hand dexterity. The findings aim to inform neuromodulation strategies for motor rehabilitation.