Determining The Suitability Of C2C12 And Hek293 In Dual Luciferase Assay (Dla) For Acvr1 (Alk2) And Tgfbr1 (Alk5)
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Aside from having high potency towards ACVR1/ALK2, inhibitor compounds ideally should be highly selective and not target other members of the Transforming Growth Factor beta (TGFb) superfamily. TGFBR1/ALK5 is selected for off-target screening because of its potential role in cardiac functions.
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2018-05-02



