Hematology and plasma biochemistry in rats fed with diets enriched with fatty fishes from Amazon region

OBJECTIVE: Rats fed diets enriched with fatty fish from the Amazon region had Hematology and plasma biochemistry analyzed. METHODS: Forty Wistar rats were divided into four groups: control group fed a standard diet; mapará group fed a diet enriched with Hypophthalmus edentatus; matrinxã group fed a diet enriched with Brycon spp.; and tambaqui group fed a diet enriched with Colossoma macropomum. After thirty days the rats had an red blood count and plasma biochemistry. RESULTS: Hematocrit and hemoglobin levels were higher in rats fed tambaqui and matrinxã than in those fed the standard diet of mapará. However, mapará increased cholesterol, especially low-density lipoprotein cholesterol and high-density lipoprotein cholesterol. All fish-enriched diets reduced triacylglycerols. CONCLUSION: Diets enriched with fatty fish from the Amazon region reduce triacylglycerol and increase high-density lipoprotein cholesterol, especially the diet enriched with tambaqui. Tambaqui and matrinxã affected hematocrit and hemoglobin levels, but not mapará. Further research is needed to determine the benefits of diets enriched with fatty fish from the Amazon region.【研究目的】本研究旨在对喂食亚马逊地区高脂鱼类饲料的大鼠开展血液学与血浆生化指标分析。【研究方法】将40只Wistar大鼠随机分为4组：对照组喂食标准饲料；马巴脂鲤（Hypophthalmus edentatus）组喂食富含马巴脂鲤的饲料；马廷沙（Brycon spp.）组喂食富含该属鱼类的饲料；坦巴基鲳（Colossoma macropomum）组喂食富含坦巴基鲳的饲料。饲养30天后，采集大鼠血液进行红细胞计数与血浆生化指标检测。【研究结果】相较于喂食标准饲料与马巴脂鲤饲料的大鼠，喂食坦巴基鲳与马廷沙饲料的大鼠红细胞比容与血红蛋白水平更高。但马巴脂鲤饲料可升高胆固醇水平，尤以低密度脂蛋白胆固醇与高密度脂蛋白胆固醇升高最为明显。所有富含鱼类的饲料均可降低血浆甘油三酯水平。【研究结论】喂食亚马逊地区高脂鱼类饲料可降低大鼠血浆甘油三酯水平并升高高密度脂蛋白胆固醇水平，其中以坦巴基鲳饲料的效果最为显著。坦巴基鲳与马廷沙饲料可影响大鼠红细胞比容与血红蛋白水平，而马巴脂鲤饲料则无此作用。未来仍需开展进一步研究，以明确亚马逊地区高脂鱼类饲料的健康益处。