Transcriptome wide target profiling for miR-23b and miR-27a.

Whole transcriptome Identification of direct targets of miR-23b and miR-27a using biotinylated pull-downs found that both miRNAs have roles relevant to the mammalian cell cycle and cancer. HEK293T cells were transfected with biotinylated miRNAs (either miR-23b or miR-27a). The miRNAs and target mRNA were pulled down with streptavidin and compared to the input control.