In Silico Characterization of the Sinoatrial Node (v2.0)

B2FIND2026-04-28 收录

心脏电生理建模

窦房结仿真

数据链接：

https://b2find.eudat.eu/dataset/a6a0b936-6279-51b9-9e5d-332527646055 数据链接链接失效反馈

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资源简介：

In silico experiments to study the sinoatrial node characteristics. The experiment script is able to modify several electrophysiological parameters using as an input a vtk file.

Conductances and APD 90 of isolated cells in the regions of the model.

心脏电生理建模

离子通道

gt,max, gCaL,max, gKr,max, gK1,max: the maximum conductance of It, ICaL, IKr and IK1 currents, respectively.

NIAID Data Ecosystem50

Data_Sheet_5_A Mathematical Model of the Mouse Atrial Myocyte With Inter-Atrial Electrophysiological Heterogeneity.docx

心脏电生理建模

心房心律失常

Biophysically detailed mathematical models of cardiac electrophysiology provide an alternative to experimental approaches for investigating possible ionic mechanisms underlying the genesis of electric

NIAID Data Ecosystem30

Data_Sheet_2_Mechanisms Underlying Interactions Between Low-Frequency Oscillations and Beat-to-Beat Variability of Celullar Ventricular Repolarization in Response to Sympathetic Stimulation: Implications for Arrhythmogenesis.zip

心脏电生理建模

心律失常机制

Background and Objectives: Enhanced beat-to-beat variability of ventricular repolarization (BVR) has been linked to arrhythmias and sudden cardiac death. Recent experimental studies on human left vent

NIAID Data Ecosystem20

Heart failure ionic remodeling.

心脏电生理建模

心力衰竭离子重塑

Changes in original Grandi et al. (GPB) [34] and O'Hara et al. (ORd) [35] models to simulate heart failure (HF) phenotype. The modified parameters are: the late Na+ current (INaL), the time constant o

NIAID Data Ecosystem40

Estimating the probabilities of rare arrhythmic events in multiscale computational models of cardiac cells and tissue

心脏电生理建模

心律失常预测

Ectopic heartbeats can trigger reentrant arrhythmias, leading to ventricular fibrillation and sudden cardiac death. Such events have been attributed to perturbed Ca2+ handling in cardiac myocytes lead

Figshare2017-11-17 更新20

In Silico Characterization of the Sinoatrial Node (v2.0)

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