In a cross balanced design human subjects were given one week of sufficient sleep and insufficient sleep (6 h per day). Following each of these conditions they were then kept awake for a day, a night
Sleep is essential for overall health, and its disruption is linked to increased risks of metabolic, cognitive, and cardiovascular dysfunctions; however, the mechanisms remain poorly understood. Using
The sleep deprivation experiment was done in wild flies or in pumilio knockdown expression (using RNA interference). Pumilio seems critical for the homeostatic response to sleep deprivation.When wild