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C-terminal deletion-induced condensation sequesters AID from IgH targets in immunodeficiency

NIAID Data Ecosystem2026-03-13 收录

免疫缺陷

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数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP286833 数据链接链接失效反馈

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资源简介：

C-terminal-deleted AID mutants fail to target IgH locus in vivo

应用场景：

创建时间：

2022-04-25

结构生物学

抗体工程

Llama nanobody n02 raised against EAEC T6SS TssM Descriptor: Llama nanobody n02 VH domain Authors: Nguyen, V.S, Desmyter, A, Le, T.T.H, Durand, E, Kellenberger, C, Douzi, B, Spinelli, S, Cascales, E,

Protein Data Bank Japan2024-10-16 更新60

Table S1 - High Affinity Humanized Antibodies without Making Hybridomas; Immunization Paired with Mammalian Cell Display and In Vitro Somatic Hypermutation

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药物研发

List of primers used for amplification of CDRH3 diversity from immunized mice. Uppercase nucleotides represent Eag I (CGGCCG) and Nhe I (GCTAGC) Type II restriction sites for cloning purposes. Lowerca

Figshare2015-12-02 更新30

DataSheet_1_A Novel Anti-Kv10.1 Nanobody Fused to Single-Chain TRAIL Enhances Apoptosis Induction in Cancer Cells.zip

癌症靶向治疗

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Antibody-based therapies hold promise for a safe and efficient treatment of cancer. The identification of target tumor cells through a specific antigen enriched on their surface and the subsequent del

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ADAPT consensus Z-scores used in VHH-72 mutation selection.

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突变体筛选

ADAPT consensus Z-scores used in VHH-72 mutation selection.

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Broad neutralizing HIV antibodies. Human immunodeficiency virus 1

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Identify immunogens for broadly neutralizing HIV-1 antibodies

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