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Cultivation media are a substantial part of many fields of life sciences and are key for successful cultivation and therefore achieving a deeper understanding of microorganisms. Despite their fundamental importance, cultivation media as data resource are mostly neglected, especially in terms of standardization and availability. We present MediaDive (https://mediadive.dsmz.de), a comprehensive and expert-curated cultivation media database, which comprises recipes, instructions and molecular compositions of almost 3,200 standardized cultivation media for more than 40,000 microbial strains from all domains of life. MediaDive is designed to enable broad range applications from every-day-use in research and diagnostic laboratories to knowledge-driven support of new media design and artificial intelligence-driven data mining. A number of intuitive search and comparison tools is fostering these approaches. External user engagement is covered by a dedicated media builder tool.

培养基是生命科学诸多领域的核心组成部分,亦是实现微生物成功培养、进而深入解析微生物特性的关键要素。尽管其具有基础性重要意义,但培养基作为数据资源却长期被忽视,尤其在标准化与可及性层面问题突出。我们推出了MediaDive(https://mediadive.dsmz.de)——一款经专家精心甄选整理的综合性培养基数据库,收录了覆盖生命各域的4万余株微生物菌株对应的近3200种标准化培养基的配方、操作指南与分子组成信息。MediaDive的设计初衷是覆盖多元应用场景:从科研与诊断实验室的日常使用,到以知识为驱动的新型培养基开发辅助,再到人工智能驱动的数据挖掘工作。多款直观易用的搜索与比对工具可为上述各类应用提供有力支撑。平台配备专属培养基构建工具,以支持外部用户参与创作,提升用户互动活跃度。

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背景与挑战
背景概述
MediaDive是一个综合性培养基数据库,提供超过3,000种标准化培养基的详细配方和组成信息,覆盖数万种微生物菌株。它旨在支持从实验室日常使用到数据挖掘的多种应用,并包含直观的搜索和比较工具。
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