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M6A Demethylase FTO-mediated downregulation of DACT1 mRNA stability promotes Wnt signaling to facilitate osteosarcoma progression

NIAID Data Ecosystem2026-05-02 收录

骨肉瘤进展

m6A表观转录组学

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE189880 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

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创建时间：

2024-11-30

m6A表观转录组学

感染免疫调控

N6-methyladenosine (m6A) is a dynamic post-transcriptional RNA modification influencing all aspects of mRNA biology. Here, we examined cellular m6A epitranscriptomes during P.aeruginosa infection to i

NIAID Data Ecosystem80

m6A meRIP-Seq from Ythdf2CKO pre-leukemic cells. m6A meRIP-Seq from Ythdf2CKO pre-leukemic cells

m6A表观转录组学

急性髓系白血病

The mRNA m6A reader YTHDF2 is overexpressed in a broad spectrum of human acute myeloid leukemias (AML). To understand the role of YTHDF2 in AML, we generated m6A meRIP-seq libraries form Ythdf2fl/fl;

NIAID Data Ecosystem30

Analysis of N6-methyladenosine Methylation Modification in Fructose-induced Non-alcoholic Fatty Liver Disease [RNA-seq2]

m6A表观转录组学

非酒精性脂肪性肝病机制

Improvements in living standards have led to non-alcoholic fatty liver disease (NAFLD), one of the most common chronic liver diseases worldwide. Recent studies have shown that N6-methyladenosine (m6A)

NIAID Data Ecosystem20

A study of m6A modification controls the innate immune response to infection by targeting type I interferons

m6A表观转录组学

先天免疫调控

Full immunoblots images for cropped gels which appear in the paper.

NIAID Data Ecosystem70

A novel RNA m6A modulator Zc3h13 plays an anchor role in facilitating nuclear RNA methylation and mouse embryonic stem cell self-renewal

m6A表观转录组学

胚胎干细胞自我更新

N6-methyladenosine (m6A) is an abundant modification in eukaryotic mRNA, regulating mRNA dynamics by influencing mRNA stability, splicing, export and translation. Recent studies discovered m6A methylt

NIAID Data Ecosystem20

M6A Demethylase FTO-mediated downregulation of DACT1 mRNA stability promotes Wnt signaling to facilitate osteosarcoma progression

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