Tandem Conjugate Reduction−Aldol Cyclization Using Stryker's Reagent
收藏NIAID Data Ecosystem2026-03-06 收录
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Conjugate reduction by Stryker's reagent to form copper enolates, followed by intramolecular aldol cyclization, successfully generated five- and six-membered carbocycles in one pot efficiently. This tandem reaction is generally diastereoselective and provides good yields of the β-hydroxyketones without any dehydration at low temperatures.
创建时间：
2016-08-20
