Caspase-6 is a member of the executioner caspases and known to play a role in innate and adaptive immune processes. However, its role in infectious diseases has rarely been addressed yet. We here exam
This network was assembled automatically by INDRA (http://indra.bio) by processing all available biomedical literature with multiple machine reading systems, and integrating curated pathway databases.
Since interleukin-6 (IL-6) may promote Th2 responses, we infected BALB IL-6-deficient (IL-6(−/−)) mice with Leishmania major. There was not a significant difference between the courses of infection (l
We have conducted a cell-specific pathway analysis of the latest GWAS in multiple sclerosis (MS); which analyzed a total of 47,351 cases and 68,284 healthy controls and found more than 200 non-MHC gen
Cells were stimulated with 20 µg/ml of peptide. 1Experiments were performed 2–4 times and means are presented. All values for peptide treated cells represent significant induction relative to the untr