Statistics estimates and P values for major haplotypes showing significant associations at the 0.05 level with at least one smoking-related phenotype under the additive and dominant models in the total sample.

(1) SI = smoking initiation; SQ = smoking quantity; SC = smoking cessation; (2) Significant associations at the 0.05 level before Bonferroni correction for multiple testing are given in bold; (3) Superscripts indicate the genetic model used: a = additive; d = dominant; (4) For each sample, age, sex, and geographic area were used as covariates.