Genome-wide mapping of DNA re-replication in S. cerevisiae

To maintain genomic stability, re-initiation of eukaryotic DNA replication within a single cell cycle is blocked by multiple mechanisms that inactivate or remove replication proteins after G1 phase为维持基因组稳定性，单个细胞周期内真核生物DNA复制的重新起始会被多种机制阻断，这类机制会在G1期（G1 phase）后使复制蛋白失活或予以清除。