DYRK2 knockout mice exhibit fetal growth retardation
收藏Alliance of Genome Resources2026-08-01 收录
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We generated DYRK2-deficient mice using the CRISPR/Cas9 genome editing method and demonstrated that loss of DYRK2 gene causes fetal growth retardation and neonatal lethality at birth. Total RNA from DYRK2-/- whole embryo was compared with those of WT mice by microarray. mRNA expression of whole embryo from DYRK2 knockout mice was compared with those of WT mice.
