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Paired VDJ and transcriptome single cell sequencing in LMP2 multimer-positive human T cells treated with anti-PD-L1 and anti-TIM3 antibodies.. Paired VDJ and transcriptome single cell sequencing in LMP2 multimer-positive human T cells treated with anti-PD-L1 and anti-TIM3 antibodies.

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NIAID Data Ecosystem2026-03-12 收录
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We report the change in gene expression profile paired to clonotype profiling in single cells from LMP2 multimer-positive human T cells generated following weekly stimulations with antigen-pulsed dendritic cells and subjected or not to PD-L1/TIM3 double blockade. Overall design: VDJ and transcriptome scRNA-sequencing at day 21 and 28 in LMP2 multimer FACS-sorted positive fractions of human T cells cultured with or without anti-PD-L1 and anti-TIM3 antibodies from 3 healthy donors.

创建时间:
2021-08-09
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