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TDP-1, the C. elegans ortholog of TDP-43, limits the accumulation of double stranded RNA

ChEBI2014-11-19 更新2026-07-21 收录

TDP-43蛋白功能

线虫模型RNA代谢调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-61581 数据链接链接失效反馈

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TDP-1, the C. elegans ortholog of TDP-43, limits the accumulation of double stranded RNA

应用场景：

创建时间：

2014-11-19

肿瘤miRNA调控

TDP-43蛋白功能

MicroRNAs (miRNAs) play important roles in a wide range of cellular processes. Aberrant regulation of miRNA genes contributes to human diseases, including cancer. The TAR DNA binding protein 43 (TDP-4

NIAID Data Ecosystem60

Loss of function mutations in TDP-43 modifier genes.

神经退行性疾病遗传

TDP-43蛋白功能

Loss of function mutations in TDP-43 modifier genes.

Figshare2019-12-13 更新40

RNAseq sequences of the study "Transactive response DNA-binding Protein (TARDBP/TDP-43) regulates early HIV-1 entry and infection" (2/2)

RNA测序分析

TDP-43蛋白功能

Each pair of FASTQ files corresponds to a specific sample condition: Condition Sample FASTQ name R1 FASTQ name R2 TDP-43 siRNA D RNASEQ-AVF9 RNASEQ-AVF9_S1_R1_001.fastq.gz RNASEQ-AVF9_S1_R2_001.fastq.

Zenodo2022-01-25 更新30

TDP-43 dysfunction restricts dendritic complexity by inhibiting CREB activation and altering gene expression. TDP-43 dysfunction restricts dendritic complexity by inhibiting CREB activation and altering gene expression

TDP-43蛋白功能

神经元树突发育

Identified TDP-43 targets in rat cortical neurons, many related to the CREB pathway Overall design: First application of TRIBE in mammalian system, used human ADAR2 catalytic domain for the experiment

NIAID Data Ecosystem50

Disruption of TDP-43 inhibits stemness of mammary epithelial cells

细胞干性调控

TDP-43蛋白功能

Here, we sought to investigate the effects of TDP-43 on proliferation and stemness of mammary epithelial cells (MECs). The results demonstrated that TDP-43 expression levels were ubiquitous in mouse m

NIAID Data Ecosystem30

TDP-1, the C. elegans ortholog of TDP-43, limits the accumulation of double stranded RNA

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