Methylation treated as a continuous outcome (M-values: PBC and COMBAT on chip) and menarcheal age category (>11 vs. ≤11 years) treated as a categorical exposure. Adjusting for age at blood collection,
Age at menarche GWAS meta-analysis from Singapore Chinese subjects. Data includes rsid, chr, pos, other_allele, test_allele, p_meta, beta_meta, se_meta, p_het, i2, p_SCHSDiscovery, p_SCHSReplication a
Menarche is the first occurrence of menstrual bleeding and one of the most important events of female puberty. Alarmingly, over the last several decades, the mean age at menarche (AAM) has decreased.