Asymmetric Synthesis of Cyclopenta[3,4]pyrroloindolones <i>via N</i>-Heterocyclic Carbene-Catalyzed Michael/Aldol/Lactamization Cascade Reaction
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资源简介:
The N-heterocyclic carbene-catalyzed asymmetric Michael/aldol/lactamization cascade reaction of enals and indole-derived enones for the synthesis of functionalized cyclopenta[3,4]pyrroloindolones with four consecutive stereogenic centers has been achieved. The products were obtained in good yield with high diastereoselectivity and excellent enantioselectivity.
创建时间:
2017-06-02



