New Perspectives on Regulation of Peripheral Tissue Antigen Expression within the Thymus, 2019

This project investigates how loss of the chaperonin CCT influences the T-cells development in the thymus and their functions in peripheral tissues. CCT is a protein that help newly made proteins to fold correctly, and without CCT, the cells are creating an aggregate of non-functional proteins. In this project, knockout (KO) mice and normal mice were used as research material.