Data for: Role of estradiol in mediation of etomidate-caused seizure-like activity in neonatal rats

Male pups showed more severe seizure-like activities than female in P4-P6, both ICI182780 and formestane alleviated abnormalities in male rats. Etomidate caused seizure-like activity in P4-P6 could long last to P9-P11, but not P14-P16, bumetanide only alleviated abnormalities in male pups other than female in P9-P11.在P4-P6阶段，雄性幼崽的癫痫样发作活动较雌性幼崽更为严重。ICI182780与福美坦（formestane）均可缓解雄性幼鼠的异常症状。依托咪酯（etomidate）在P4-P6阶段诱导产生的癫痫样发作活动可延续至P9-P11阶段，但无法持续至P14-P16阶段；布美他尼（bumetanide）仅在P9-P11阶段可缓解雄性幼崽的异常症状，对雌性幼崽无改善效果。