The conserved Mps1 kinase corrects improper kinetochore-microtubule attachments, thereby ensuring chromosome biorientation. Yet, its critical targets in this process remain elusive. Mps1 is also invol
An EGFP-tagged full length CENP-E construct was transfected into K243R/+ MEFs. Cells were treated with MG132 for 2 hours and subjected to a cold stable microtubule assay. The images were acquired wit
The first sheet contains the molecules of (active) Tem1-GTP at the SPB in simulations of wild-type, Bfa1-SPB, and bfa1Δ cells as calculated from the ODE model of Caydasi and colleagues (2012). Spindle