Adult hematopoietic stem cells (HSCs) are predominantly quiescent and can be activated in response to acute stress such as infection or cytotoxic insults. STAT1 is a pivotal mediator of interferon (IF

NIAID Data Ecosystem50

ASCL2 is a key regulator of the proliferation-differentiation equilibrium in the esophageal epithelium

干细胞稳态调控

上皮细胞分化

The esophagus is protected from the hostile environment by a stratified epithelium, which renews rapidly. Homeostasis of this epithelium is ensured by a rare population of stem cells in the basal laye

NIAID Data Ecosystem00

Non-catalytic functions of Tet2 are essential to regulate hematopoietic stem and progenitor cell homeostasis. Non-catalytic functions of Tet2 are essential to regulate hematopoietic stem and progenitor cell homeostasis

干细胞稳态调控

Tet2非催化功能

To identify genes that are influenced by the catalytic and non-catalytic functions of Tet2 in hematopoietic stem and progenitor cells (HSPCs), we analyzed the gene expression profiles of Tet2 catalyti

NIAID Data Ecosystem60

The E3 ubiquitin ligase DDB1 controls homeostasis of hematopoietic stem and progenitor cells

干细胞稳态调控

E3泛素连接酶功能

The E3 ubiquitin ligase DDB1 controls homeostasis of hematopoietic stem and progenitor cells

ChEBI2015-07-10 更新30