Spontaneous mutation rates in strains with <i>dpb3Δ dpb4Δ</i> and mismatch repair deficiency.

The genetic experiments were performed with derivatives of the strain created by [34] and named E134 [33] obtained as described in Materials and Methods. aMutation rates are given as median of one experiment with nine independent cultures and coincide with previously published data. *For all other cases mutation rates were obtained as median of 18–45 independent cultures and determined as described in [33]. §9/9 sequenced revertants contained -1 frameshift mutation within 14A run.