Here, refers to the extracellular domain, refers to the membrane domain, and refers to the intracellular domain (see Fig 1). Note that the intracellular diffusion coefficients for Na+, K+ and are set
We investigate the hypothesis that two classes of Ca2+ currents, one quickly inactivated by Ca2+ and one slowly inactivated by voltage, contribute to bursting electrical activity in pancreatic islets.
a. Immunofluorescence analyses of CM markers, n=3. Scale bars, 50 µm.b. Transmission electron microscopy images of hCiCMs derived from hUCs at day 60, n=3. MF, myofibrils; Z, Z-bands; Mit, mitochondri
(A) ΔψP as a function of ΔψM in the presence of 4.5–16 mM glucose (solid isolines and closed squares) or 50 μM glibenclamide (dotted isolines and open circles). Two-dimensional histograms show the dis
