Mean baseline and 6 month values and the mean absolute changes in insulin sensitivity, insulin secretion and β-cell function in the subgroup of participants with prediabetes.

Baseline and 6 month data are presented as mean (SD). *A 2-factor repeated-measures regression analysis was used to assess time effects and time by treatment effect interactions on all outcome variables. †Logarithmically-transformed variables. ‡Calculated by multiplying Matsuda index by AUC for C-peptide. AUC, area under the curve; HOMA2%S, Homeostasis Model Assessment 2 index of insulin sensitivity. Mean baseline and 6 month values and the mean absolute changes in insulin sensitivity, insulin secretion and β-cell function in the subgroup of participants with prediabetes.