Enantioselective Synthesis of Polycyclic Coumarin Derivatives Catalyzed by an <i>in Situ</i> Formed Primary Amine-Imine Catalyst
收藏NIAID Data Ecosystem2026-03-07 收录
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A facile in situ formed primary amine-imine organocatalyst was developed in the asymmetric Michael addition of substituted 4-hydroxycoumarins to cyclic enones. A series of optically active polycyclic coumarin derivatives were obtained in high yields with excellent enantioselectivities up to 97% ee.
创建时间：
2011-08-19
