The endocannabinoid system (ECS) consists particularly of cannabinoid receptors 1 and 2 (CB1 and CB2), their endogenous ligands, and enzymes that synthesize and degrade their ligands. It acts in a var
Mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4) is Ser/Thr protein kinase highly expressed in medulloblastoma (MB) patient samples which promotes cell migration and invasiveness downs
To identify the mutants which can be buffered by Hsp90, we applied EMS mutagenesis to created random mutations. By bulk segregant analysis, we can know the candidate casual gene responsible Hsp90-buff