Comparative gene expression analyses identify luminal and basal subtypes of canine invasive urothelial carcinoma that mimic patterns in human invasive bladder cancer. Canis lupus familiaris

Microarrays were used to assay the gene expression profile of canine normal bladder from non-tumor bearing dogs and compared to that of bladder tumor in dogs. Overall design: Work was conducted to compare gene expression array results between tissue samples from iUC and normal bladder in dogs. Affymetrix canine 2.0 chips were used to conduct the experiment.