Copper-Mediated α‑Trifluoromethylation of N‑Phenylcinnamamides Coupled with Dearomatization: Access to Trifluoromethylated 1‑Azaspiro[4.5]decanes
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Copper-mediated intramolecular trifluoromethylation of N-phenylcinnamamides coupled with cyclization and dearomatization was used to construct various trifluoromethylated 1-azaspiro[4.5]decanes in moderate to high yields and with excellent regioselectivity and diastereoselectivity.
创建时间：
2016-02-16
