spliceNest

SpliceNest is a web based graphical tool to explore gene structure, including alternative splicing, based on a mapping on the EST consensus sequences (contigs) from GeneNest to the complete human genome. SpliceNest is integrated with GeneNest and the SYSTERS protein sequence cluster set in one framework, permitting an overall exploration of the whole sequence space covering protein, mRNA and EST sequences, as well as genomic DNA.SpliceNest是一款网页端图形化分析工具，可用于探究基因结构（包含可变剪接），其分析基于将来自GeneNest的表达序列标签（EST）一致性序列（重叠群contigs）比对至完整人类基因组的结果。该工具已与GeneNest以及SYSTERS蛋白质序列聚类集集成至同一分析框架中，能够实现对涵盖蛋白质、信使RNA（mRNA）、表达序列标签（EST）序列以及基因组DNA的全序列空间的全方位探索。

搜集汇总

背景与挑战

背景概述

SpliceNest是一个基于Web的图形工具，用于可视化基因结构和选择性剪接，其基础是GeneNest EST Contigs到基因组的映射。该工具整合了GeneNest和SYSTERS框架，支持人类、小鼠等多个物种的数据探索。