A four-year data of 4,526 presumptive TB cases diagnosed using GeneXpert. Data included MTB cases, Rifampicin Resistance TBs and TB-HIV co-infection cases in a Nigerian Tertiary Hospital
Drug-resistance to tuberculosis remains a major public health threat. Here, we report two cases of extended-spectrum XDR (XXDR) tuberculosis, resistant to most first and second-line agents. Correlatio
‘*’ resistance determined at amikacin (AMK, 6 μg/ml), kanamycin (KAN, 6 μg/ml) and capreomycin (CAP, 6 μg/ml), ‘wt’ wild type indicates absence of SNPs in the rrs 1400 gene, the number in parenthesis
TB seek is a new nanopore sequencing based test designed for simultaneous TB identification and antibiotic resistance genotyping. The TBseek test is based on multiplex PCR, targeting specific genes fo
Crystal structure of Eis from Mycobacterium tuberculosis in complex with inhibitor SGT416 Descriptor: DIMETHYL SULFOXIDE, N,N-diethyl-2-[(8-fluoro-5-methyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)sulfanyl