A sumoylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis

ChEBI2011-12-08 更新2026-07-21 收录

癌症分子机制

转录调控

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-34055 数据链接链接失效反馈

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A sumoylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis

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2011-12-08

OBF1 and Oct factors control the germinal center transcriptional program [Mouse]. OBF1 and Oct factors control the germinal center transcriptional program [Mouse]

转录调控

生发中心

OBF1 is a specific coactivator of the POU family transcription factors OCT1 and OCT2. OBF1 and OCT2 are B cell-specific and indispensable for germinal center (GC) formation, but their mechanism of act

NIAID Data Ecosystem60

DataSheet4_PRR11 promotes cell proliferation by regulating PTTG1 through interacting with E2F1 transcription factor in pan-cancer.zip

癌症分子机制

细胞周期调控

The upregulated proline rich 11 (PRR11) plays a critical role in cancer progression. The relevant biological functions of PRR11 in pan-cancer development are not well understood. In the current study,

NIAID Data Ecosystem30

Table_1_ABCC6 Knockdown Fuels Cell Proliferation by Regulating PPARα in Hepatocellular Carcinoma.xls

癌症分子机制

ABCC6基因功能

The ATP binding cassette (ABC) transporter family is ubiquitous in eukaryotes, specifically in vertebrates, and plays a crucial role in energy homeostasis, cell signaling, and drug resistance. Accumul

NIAID Data Ecosystem20

Additional file 3 of ALKBH5 prevents hepatocellular carcinoma progression by post-transcriptional inhibition of PAQR4 in an m6A dependent manner

癌症分子机制

依赖性基因调控

Additional file 3. Overexpression of ALKBH5 decreased the proliferation capacity in 2 HCC cell lines, while co-overexpressed of PAQR4 reverted this phenomenon (A and B). Overexpression of ALKBH5 decre

NIAID Data Ecosystem30

Expression and transcriptional regulation dynamics of hepatic lincRNAs

肝脏lincRNA表达谱

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Gene expression in adult male and female mouse liver was assayed by RNA-seq, as part of a study on hepatic lincRNAs. Total liver RNA was prepared from 12 individual male and 12 individual female mice.

Alliance of Genome Resources20

A sumoylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis

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