BackgroundSystematic reviews of treatment interventions in stable or chronic conditions often require the synthesis of clinical trials with a cross-over design. Previous work has indicated that method
OBJECTIVES: To assess the methodological quality of intention to treat analysis as reported in randomised controlled trials in four large medical journals. DESIGN: Survey of all reports of randomised
1—Was the study described as randomized?2—Was the method of randomization described and appropriate?3—Was the study described as double blind?4—Was the method of blinding described and appropriate?5—W