Prp8 Retinitis Pigmentosa Mutants Cause Defects in the Transition between the Catalytic Steps of Splicing

The essential process of pre-mRNA splicing must occur with high fidelity and efficiency for proper gene expression前信使RNA剪接（pre-mRNA splicing）这一核心必需过程，必须以高保真度与高效率完成，以保障基因表达的正常运作。