Cross-platform toxicogenomics for the prediction of nongenotoxic hepatocarcinogenesis in rat

NIAID Data Ecosystem2026-03-11 收录

毒物基因组学

肝致癌性预测

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE53085 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2019-10-04

DrugMatrix

毒物基因组学

化学物毒性预测

DrugMatrix是世界上最大的毒物基因组学参考资源数据库之一，包含600多种化合物的毒物基因组学谱数据。该数据库与ToxFX报告系统配合使用，可帮助用户快速创建完全注释的报告，提高毒理学评估效率，减少确定外源性物质潜在毒性所需的时间。DrugMatrix基因表达数据存储在Gene Expression Omnibus数据库中，包含多种微阵列数据。

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Analyses of transcriptomic responses generated by hepatocarcinogens in a battery of liver-based in vitro models. Analyses of transcriptomic responses generated by hepatocarcinogens in a battery of liver-based in vitro models

毒物基因组学

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For assessing the cancer-causing potential for humans of a chemical compound, the conventional approach is the use of the 2-year rodent carcinogenicity bioassay, thus alternatives such as in vitro tox

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Nitrophenol (p-nitrophenol) treatment with 1.5 mM for 2 h. Saccharomyces cerevisiae

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The number and type of synthetic chemicals that are being produced worldwide continues to increase significantly. While these industrial chemicals provide numerous benefits, there is no doubt that som

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Non-genotoxic Hepatocarcinogens

毒理基因组学

肝致癌性预测

There is no accurate and well-validated short-term test for non-genotoxic carcinogens, necessitating an expensive two year rodent bioassay before a risk assessment can begin. We have developed a short

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West Virgina Chemical Spill: 5-Day Rat Toxicogenomic Studies. West Virgina Chemical Spill: 5-Day Rat Toxicogenomic Studies

毒物基因组学

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As part of the West Virginia Chemical Spill research program, NTP evaluated three chemicals that were spilled into the Elk Rever in West Virginia for their ability to cause toxicity or biological chan

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Cross-platform toxicogenomics for the prediction of nongenotoxic hepatocarcinogenesis in rat

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