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Effect of Cas3-base editor expression in S. cerevisiae

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NIAID Data Ecosystem2026-05-01 收录
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We evaluated the ability of different Cas3-base editors to introduce cytidine deaminations around a specifiable target site in the S. cerevisiae genome. We tested four Cas3-base editors as well as wild type Cas3 targeted to two different target sites or untargeted and assessed the respective on-target and off-target activity.

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2023-05-22
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