Agile Protein Interactomes Dataserver

APID Interactomes (Agile Protein Interactomes DataServer) provides information on the protein interactomes of numerous organisms, based on the integration of known experimentally validated protein-protein physical interactions (PPIs). The interactome data includes a report on quality levels and coverage over the proteomes for each organism included. APID integrates PPIs from primary databases of molecular interactions (BIND, BioGRID, DIP, HPRD, IntAct, MINT) and also from experimentally resolved 3D structures (PDB) where more than two distinct proteins have been identified. This collection references protein interactors, through a UniProt identifier.

APID蛋白质交互组数据库（Agile Protein Interactomes DataServer，敏捷蛋白质交互组数据服务器）通过整合经实验验证的蛋白质-蛋白质物理相互作用（protein-protein physical interactions，PPIs），为多个物种提供蛋白质交互组相关信息。该数据集涵盖所收录各物种的蛋白质组覆盖度与数据质量评估报告。APID整合了分子相互作用一级数据库（BIND、BioGRID、DIP、HPRD、IntAct、MINT）中的PPIs数据，同时纳入经实验解析且可识别至少两种不同蛋白质的三维结构（PDB）数据。本数据集依托通用蛋白质资源（UniProt）标识符关联蛋白质交互伴侣分子。

搜集汇总

背景与挑战

背景概述

APID Interactomes是一个整合了多种生物体蛋白质相互作用组信息的数据库，它基于已验证的蛋白质物理相互作用数据，并整合了多个主要分子相互作用数据库及PDB结构数据。该数据集提供了相互作用的质量水平和蛋白质组覆盖度报告，且所有蛋白质相互作用均通过UniProt标识符进行引用。