Characterization Type II-C CRISPR Cas systems from Defluviimonas sp. 20V17 and Pasteurella pneumotropica. Illumina sequencing reads from PpCas9 specificity tests.

NIAID Data Ecosystem70

Study on genome editing tool

体内基因编辑

基因工程工具开发

To develop a genome tool with high efficiency in in vivo study

NIAID Data Ecosystem40

Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications

CRISPR-Cas3结构机制

基因工程工具开发

Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications Descriptor: AcrIC9, Cas11, Cas5, ... Authors: Hu, C, Nam, K.H, Ke, A. Deposit date: 2023-02-22

Protein Data Bank Japan2025-05-21 更新80

Engineering a transposon-associated TnpB-omegaRNA system for efficient gene editing and phenotypic correction of a tyrosinaemia mouse model

基因工程工具开发

疾病模型研究

Transposon-associated ribonucleoprotein TnpB is known to be the ancestry endonuclease of diverse Cas12 effector proteins from type-V CRISPR system. Given its small size (409 aa), it is of interest to

NIAID Data Ecosystem50

Continuous evolution of mitochondrial and nuclear TALE base editors with improved activity and expanded targeting scope

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