The Mitochondrial Calcium Uniporter controls skeletal muscle mass in vivo

ChEBI2015-03-05 更新2026-07-21 收录

骨骼肌收缩调控

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-60931 数据链接链接失效反馈

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The Mitochondrial Calcium Uniporter controls skeletal muscle mass in vivo

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2015-03-05

The conserved aspartate ring of MCU mediates MICU1 binding and regulation in the mitochondrial calcium uniporter complex

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蛋白质相互作用调控

The mitochondrial calcium uniporter is a Ca2+ channel that regulates intracellular Ca2+ signaling, oxidative phosphorylation, and apoptosis. It contains the pore-forming MCU protein, which possesses a

DataONE2020-06-24 更新60

The vitamin D receptor (VDR) autonomously regulates skeletal muscle mass

骨骼肌收缩调控

维生素D受体

Vitamin D (VitD) deficiency is estimated to affect ~40% of the world’s population. Notably, VitD deficiency has been associated with impaired muscle maintenance and insulin resistance. VitD exerts its

NIAID Data Ecosystem20

Mitochondrial Calcium Uptake Methods

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分子生物学实验方法

Dataset for mitochondrial calcium influx methods for DOI: 10.3791/57225

Figshare2022-04-29 更新10

Evidence supporting the MICU1 occlusion mechanism and against the potentiation model in the mitochondrial calcium uniporter complex. Tsai et al.

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蛋白质合成机制

Unprocessed raw Western-blot or BN-PAGE images used in the figures in Tsai et al., PNAS, 2023.

NIAID Data Ecosystem50

Mitochondrial Calcium Exchange links Metabolism with the Epigenome to Control Cellular Differentiation (ATAC-seq). Mitochondrial Calcium Exchange links Metabolism with the Epigenome to Control Cellular Differentiation (ATAC-seq)

细胞分化表观遗传调控

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Fibroblast to myofibroblast differentiation is crucial for the initial healing response but excessive myofibroblast activation leads to pathological fibrosis. Therefore, it is imperative to understand

NIAID Data Ecosystem20

The Mitochondrial Calcium Uniporter controls skeletal muscle mass in vivo

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