Data from: Parental and offspring larval diets interact to influence life history traits and dengue virus infection of offspring in Aedes aegypti

The environmental conditions experienced by parents can influence offspring phenotype along with the conditions experienced by offspring. These parental effects are clear in organisms that display parental care and are less clear in other organisms. Here we consider effects of parental and offspring larval nutrition on offspring development time, survivorship, and infection with dengue virus in Aedes aegypti, the mosquito vector of dengue, chikungunya, yellow fever and Zika. Parents were raised on either high or low larval detritus inputs with subsequent offspring being divided into two groups, one receiving high nutrients and the other low. Low nutrient females from low nutrient parents (LL) developed significantly slower than those from high nutrient parents (HL). Females from all parent by offspring nutrient treatment groups were equally likely to become infected with dengue virus at 24 hours, 3 days, and 14 days. After 14 days, high nutrient females from low nutrient parents (LH) had 11 times higher viral titers and more disseminated infections than females from high nutrient parents (HH) nutrient parents. These results suggest that carryover environmental stress from the parental generation can influence life histories and arbovirus infection in Ae. aegypti females. We found males to be robust to the life history parameters measured, suggesting sex-specific differences which may relate to their lower nutrient requirements for metamorphosis.双亲所经历的环境条件，以及子代自身所经历的环境条件，均可对子代表型产生影响。这类双亲效应在存在育幼行为的生物中表现显著，而在其他类群中则相对不明显。本研究以登革热、基孔肯雅热、黄热病及寨卡病毒的传播媒介——埃及伊蚊（Aedes aegypti）为研究对象，探讨双亲与子代的幼虫营养条件对子代发育时长、存活率以及登革病毒感染情况的影响。实验双亲的幼虫阶段分别接受高、低两种腐屑营养供给，其后裔子代被分为两组：一组饲喂高营养饵料，另一组饲喂低营养饵料。低营养组子代雌蚊（双亲均为低营养组，记为LL）的发育速度显著慢于双亲为高营养组的低营养组子代雌蚊（记为HL）。在感染后24小时、3天及14天三个时间点，所有双亲-子代营养处理组合的雌蚊，其登革病毒感染率均无显著差异。感染14天后，双亲为低营养组的高营养组子代雌蚊（记为LH），其体内病毒载量是双亲为高营养组的高营养组子代雌蚊（记为HH）的11倍，且播散性感染发生率更高。上述结果表明，亲代遗留的环境胁迫可影响埃及伊蚊雌蚊的生活史特征以及虫媒病毒感染情况。本研究发现雄蚊对所检测的生活史参数无显著响应，这提示存在性别特异性差异，该差异可能与雄蚊变态发育所需的营养需求更低有关。