Ph.D. Thesis "Species spectrum and biological properties of bacterial and fungal causative agents of health-care-associated infections and study of antimicrobial activity against them using 4-thiazolidinone derivatives."

Thesis for the degree of Ph.D. in the specialty 222 Medicine (Area of knowledge 22 Health care). - Danylo Halytskyy Lviv National Medical University, Ministry of Health of Ukraine, Lviv, 2021. Yulian Konechnyi "Species spectrum and biological properties of bacterial and fungal causative agents of health-care-associated infections and study of antimicrobial activity against them using 4-thiazolidinone derivatives." - Qualifying scientific work on the rights of the manuscript. In Ukrainian. The thesis presents a theoretical generalization and solution of the current scientific and practical problem of health care, as determination of the structure and distribution of Healthcare-Associated Infections (HAIs) in Ukraine in recent years, features of the species spectrum of pathogens, and the spreading of antibiotic resistance, clinical and microbiological characteristics of HAIs, including those caused by rare pathogens of HAIs, as well as a search, synthesis, screening of new chemical compounds with antimicrobial and antifungal activity in order to introduce new prototypes of antimicrobial drugs.本论文为乌克兰卫生部下属的利沃夫丹尼洛·哈利茨基国立医科大学（Danylo Halytskyy Lviv National Medical University）授予的222医学专业（知识领域22：医疗保健）的博士学位论文，利沃夫，2021年。 作者尤利安·科内奇尼（Yulian Konechnyi）：《医疗保健相关感染的细菌与真菌病原体的物种谱及生物学特性，以及采用4-噻唑烷酮（4-thiazolidinone）衍生物开展抗该类病原体的抗菌活性研究》，本研究为以手稿形式提交的资格科研论文，原文为乌克兰语。 本论文针对当前医疗保健领域的科学与实际问题开展理论归纳与解决方案研究，具体包括：明确近年来乌克兰境内医疗保健相关感染（Healthcare-Associated Infections, HAIs）的流行结构与分布特征、病原体物种谱特点、抗生素耐药性的传播态势、医疗保健相关感染的临床与微生物学特征（含罕见医疗保健相关感染病原体引发的感染病例）；同时开展新型抗菌与抗真菌活性化合物的搜寻、合成与筛选工作，以期研发新型抗菌药物原型。