CLINICAL AND FUNCTIONAL ANALYSIS OF CARDIAC ARRHYTHMIAS IN PATIENTS WITH LIVER CIRRHOSIS AND THEIR PROGNOSTIC SIGNIFICANCE

Background. Liver cirrhosis is one of the leading causes of disability and death worldwide, and its effects on the cardiovascular system have attracted increasing attention in recent years. Hemodynamic, neurohumoral, and metabolic changes occurring in liver cirrhosis disrupt the electrical stability of the myocardium and create conditions for the development of various cardiac rhythm disturbances. Arrhythmias are an important factor associated with sudden cardiac death, heart failure, and a poorer overall prognosis in patients. Objective. To investigate the clinical and functional characteristics of cardiac rhythm disturbances in patients with liver cirrhosis and to assess their relationship with disease severity and prognosis. Materials and methods. The study included 80 patients with liver cirrhosis who were treated at the FAMILY DOCTORS M private clinic in 2025–2026. All patients underwent clinical examination, laboratory testing, 12-lead electrocardiography, 24-hour Holter monitoring, and Doppler echocardiography. The patients were divided into three groups according to the Child–Pugh classification. Results. As liver cirrhosis became more severe, the frequencies of QTc interval prolongation, sinus tachycardia, ventricular extrasystoles, and diastolic dysfunction increased significantly. Cardiac rhythm disturbances were particularly prominent as a high-risk indicator in the Child–Pugh C group. Conclusion. Early detection of cardiac rhythm disturbances and regular cardiological monitoring in liver cirrhosis are important for improving patient prognosis.