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One-Pot Construction of Functionalized Spiro-dihydronaphthoquinone-oxindoles via Hauser–Kraus Annulation of Sulfonylphthalide with 3‑Alkylideneoxindoles

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NIAID Data Ecosystem2026-03-10 收录
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The Hauser–Kraus annulation of sulfonylphthalide with 3-olefinic oxindole has been performed. This strategy, which involves a cascade Michael addition–Dieckmann cyclization–elimination sequence, offers rapid and convenient access to novel spiro-dihydronaphthoquinone-oxindoles in excellent yields with complete selectivity for the enolic form under mild reaction conditions.

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2017-11-20
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